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As life science manufacturing evolves at an accelerated pace, facilities must be designed to support current operations and anticipate future growth. Promega’s Chappelle Manufacturing Center (CMC) exemplifies how intentional pre-investment can enable long-term manufacturing expansion while minimizing disruption to ongoing operations.

This session at the ISPE Annual Meeting will explore how Promega, collaborating with Flad and Affiliated Engineers, Inc. (AEI), embedded flexibility into the master planning, architectural design, infrastructure, and site development of the CMC. The presentation will detail how early identification of strategic growth assumptions across both manufacturing and support functions informed planning decisions and enabled flexibility over the life of the facility, including strategically located adjacencies and intentionally oversized spaces to accommodate future systems, equipment, and processes.

Presenters will also discuss site planning strategies that support future building additions for long-term operational value. Promega will share insights on how built-in flexibility enabled recent laboratory expansions, process improvements, and the addition of new GMP manufacturing capabilities. Additional discussion will highlight considerations unique to the CMC, including planning for future automation, safety, and code implications, and a strong commitment to human-centric design principles such as access to daylight, views, and well-being. Presenters will examine the cost-versus-benefit associated with flexibility.